A 140-year-old global pharmaceutical company with headquarters in Japan adopted Aspen Plus to improve the synthesis of a new active pharmaceutical ingredient (API). Aspen Plus provided an in-depth understanding of a new API process leading to equipment improvements and optimized recipes that enabled development of a continuous process.

GlaxoSmithKline (GSK) wanted to review the structure of its batch production record and associated workflows as part of a continuous improvement process. Reducing batch review time usually results in faster batch cycle time, meaning higher throughput at the production facility and faster cash-to-cash cycle time. AspenTech was selected for this process due to integration with other solutions, such as Aspen InfoPlus.21® and GSK’s existing plant automation software (DCS). The pilot project was a resounding success, reducing order preparation time by 95% and record review time by over 50%.