Aspen Chromatography

Simulate Chromatography While Improving Process Design.

Aspen Chromatography is a comprehensive flowsheet simulator for batch and continuous chromatographic separation processes, compatible with both Aspen Plus and Aspen Plus Dynamics.
Aspen Chromatography
Learn and Apply
Card image

Identify optimal designs and improve profitability.

Aspen Chromatography allows engineers and scientists to model and understand the chromatographic separation and purification processes normally found in the pharmaceutical, biotechnology, fine chemical, and food product businesses. Reduce recycle flowrates and improve extract and raffinate purities, resulting in higher chromatographic separation process yields and improved profitability—in less development time.

Card image

Reduce costs with rigorous rate-based chromatography column models.

Choose from a wide range of kinetic models, including transport dispersive, equilibrium dispersive, lumped pore, and general rate model. Utilize standard equilibrium/isotherm models that allows pure component or multi-component/competitive behavior. Use a highly configurable energy balance to account for non-isothermal behavior, conduction, heat loss, and wall effects.


Card image

Decrease scale-up time with packaged models.

With Aspen Chomatography, use flexible models to study other Simulated Moving Bed (SMB) variants such as Intermittent SMB, PowerFeed, ModiCon, and Thermal Gradient. Benefit from rigorous dynamic simulation that enables the analysis of time-dependent internal and product compositions and steady-state True Moving Bed (TMB) mode for rapid chromatographic separation process evaluation.

Card image

Manage cycles and improve throughput.

Define any number of independently operated cycles, each containing several chromatographic separation process steps (e.g., production, purge, equalization, and repressurization). Control process steps by timer or by monitored events.

Card image

Utilize the world’s largest database for physical properties.

Aspen Chromatography uses Aspen Properties, the world’s most comprehensive physical property database. Employ state-of-the-art activity coefficient models and equations of state, including extensive databases for a wide range of components for modeling chromatographic separations.

Card image

Get started with sample models.

Aspen Chromatography includes over 50 examples, each with brief instructions that can serve as training or a starting point for your chromatographic separation process design.

Related Products

Aspen Plus

Aspen Plus

Maximize profits using a plant-wide simulation solution that combines unparalleled accuracy and engineering collaboration with time-saving workflows.

Aspen Polymers

<p><strong><br /></strong></p><p><strong>Aspen Polymers<sup>®</sup></strong> is the market-leading, first-principles polymer modeling technology for accurate and reliable simulation and optimization o...

Aspen Properties

Stop manually researching and transferring physical property data. Use the industry standard for thermophysical properties modeling throughout the process lifecycle with <strong>Aspen Properties<sup>®...

Aspen Custom Modeler

Create unique process and equipment simulation models with accuracy and ease using <strong>Aspen Custom Modeler</strong>. With a simplified approach to exporting custom models into Aspen Plus<sup>®</s...

Upcoming Events